The Common Fund’s Cellular Senescence Network (SenNet) Program was established to comprehensively identify and characterize the differences in senescent cells across the body, across various states of human health, and across the lifespan. SenNet will provide publicly accessible atlases of senescent cells, the differences among them, and the molecules they secrete, using data collected from multiple human and model organism tissues. To identify and characterize these rare cells, SenNet will develop innovative tools and technologies that build upon previous advances in single cell analysis, such as those from the Common Fund’s Human Biomolecular Atlas Program. Lastly, SenNet aims to unite cellular senescence researchers by developing common terms and classifications for senescent cells.

Consortium Undergraduate Student Program News

2023 CUSP graduate Hillina Berhane recently accepted a position as a Postbac fellow for Intramural Research at the National Institutes of Health (NIH). In this role, she will conduct research at the National Institute of Neurological Disorders and Stroke, under the supervision of Dr. Avindra Nath. Her focus will be investigating the neurological effects of the human immunodeficiency virus (HIV) and its association with cellular senescence.

Hillina graduated from Virginia Commonwealth University, holding a Bachelor of Science in Psychology with a Minor in Chemistry. Having completed a pre-medicine track, she is passionate about pursuing a career in medicine, specifically in the field of Hematology/Oncology. Hillina was a student of the first SenNet CUSP internship, in which she explored her interests in cellular and molecular biology, investigating cellular senescence in aged and irradiated mice liver tissue.

She gained invaluable experiences in vast laboratory techniques, such as IHC, IF, and qPCR, learning from top experts in the field of cellular senescence. The skills and exposure that she acquired during her internship developed her into a competitive candidate for the NIH Postbac program. She looks forward to applying those skills and the knowledge she obtained to her research endeavors at NIH.

New Members: Please make sure you register for an account on SenNet and direct all questions to help@sennetconsortium.org.

You can also visit our Frequently Asked Questions page.

News

SenNet remembers Dr. Judith Campisi (1949-2024).

The SenNet Spring Meeting site is now live: click to register to attend and book your hotel room.

The Consortium Undergraduate Student Program (CUSP) has finished accepting applications for Summer 2024 Internships.

Registration open for the NIH-CZI Junior Investigators Atlas Builders Meeting on March 17-19, 2024. The conference topic is “Cellular and Molecular Human Atlases in Health and Disease.”

The 6th release of the Human Reference Atlas (HRA) is now available via https://humanatlas.io/. See details on what data, tools, training materials were updated/added in the Release Notes at https://humanatlas.io/release-notes/v2.0.

Sign up for HuBMAP’s 12/19/23 VUES Seminar with Jeremy Kriegel! Topic is: “Development of User Personas: Who is the User in Your Stories?”

The SenNet Interview Series has launched: subscribe to our YouTube channel for new interviews with Consortium scientists!

The 4DN Predictive Modeling Working Group at the University of Washington in Seattle, WA is hosting a hackathon on 3/18-3/21/24

The NIH Common Fund Human BioMolecular Atlas Program (HuBMAP) is excited to announce the 2023-2024 JumpStart Program!

Kaggle Competition Launched: “SenNet + HOA – Hacking the Human Vasculature in 3D”

HTAN Jamboree & HuBMAP Jumpstart Program

Collection of Articles Reports Advances in Building Cellular Organization Maps of the Human Body

Joao Passos‘s new publication “Spatial mapping of cellular senescence: emerging challenges and opportunities” is out now

NIH launches program to map a rare type of non-dividing cells implicated in human health and disease

Molecular Atlas of Senescent Cells Could Chart Way to Therapies for Age-Related Diseases and Cancer

Pitt teams tapped to develop ‘Google Maps’ of cells important in aging

$125 Million in Grants to Study Cellular Aging to Be Coordinated from Pittsburgh 

CMU CompBio Researchers Take Leading Roles in NIH SenNet Program

Buck Institute awarded $12.7 million from NIH to join SenNet, Cellular Senescence Network

Tissue Mapping Center for Cellular Senescence Launched at Yale Cancer Center to Study Human Lymphoid Organs

NIH supports studies on senescent cells: UW Medicine will be part of the Cellular Senescence Network to research these cells in aging and other processes.

Dr. Hemali Phatnani Awarded NIH Grant to Build 3D Atlas To Map “Senescent” Cells and Probe Their Role in Human Aging and Disease

$7.5 million to study elusive cell type important in aging, cancer, other diseases

Brown University researcher awarded NIH SenNet grant to investigate senescent cell microenvironments across multiple tissues

UT Health Science Center San Antonio among group tapped by NIH to map senescent ‘zombie’ cells in the body

Senescent Cell Tissue Mapping Will Facilitate Study of Aging and Chronic Diseases